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"It’s not just a new campaign type. It’s a whole new revenue stream."

Amazon Business Campaigns are here, and we’re already seeing game-changing results.

A short time ago, Amazon launched something big: Amazon Business Campaigns — a feature allowing advertisers to target B2B buyers directly on the platform. For brands focused on growth, this is a goldmine. And at AmpliSell, we jumped in on day one.

In this post, we’ll break down what Amazon Business Campaigns are, how they differ from traditional B2C campaigns, and how we’ve already seen incredible results by simply duplicating a high-performing B2C strategy into this new B2B environment.

What Are Amazon Business Campaigns?

Until now, Amazon sellers could offer business pricing, but ad campaigns treated all shoppers the same, whether they were individuals or companies. That’s changed.

With Amazon Business Campaigns, you can now build campaigns that target verified business customers only. Here's what’s new:

  • Business-Only Campaign Targeting: Reach only Amazon Business buyers, not everyday shoppers.

  • Business-Specific Pricing & Quantity Discounts: Incentivize bulk orders by offering tiered discounts (e.g., buy 5+, get 10% off).

  • Bid Adjustments for Business Placements: Boost your bids by up to 900% to win high-impact ad placements that show only to business buyers.

  • New Reporting Capabilities: Access performance data specific to Amazon Business placements to track efficiency.

  • Sponsored Display B2B Audience Targeting: Use new audience segments (like “Lifestyle Segment - B2B - Amazon Business”) to reach verified business accounts across Sponsored Display.

These tools give sellers the ability to capture larger, more valuable orders with smarter spend.

How It Works and Why It’s a Big Deal

Amazon Business Campaigns work like standard Sponsored Product campaigns, with one major difference: they’re built for bulk buyers.

Think office managers buying 20 desks or educational institutions outfitting entire classrooms. These aren’t casual purchases, they’re big-ticket, high-intent orders.

Even better? You're competing with fewer advertisers, and early data shows the return on ad spend (ROAS) is significantly higher.

Quick Comparison: B2C vs. B2B Campaigns

  • Targeting: B2C = everyone / B2B = business buyers only
  • Average Order Value: B2C low or medium / B2B = high (bulk orders)
  • Competition: B2C = high / B2B = lower (new feature)
  • ROAS Potential: B2C = moderate / B2B = high
  • Volume Discounts: B2C = optional / B2B = powerful incentive

Our Test: Duplicating a Successful B2C Campaign for B2B

We took one of our top-performing B2C campaigns — same keywords, same products — and duplicated it using the new B2B targeting tools. No creative overhaul. No keyword changes. Just smarter audience selection.


The results:

B2C Campaign (1 week)

  • Spend: $1,309.80
  • Sales: $11,916.91
  • ACoS: 10.99%
  • Orders: 222

B2B Campaign (same week)

  • Spend: $23.79
  • Sales: $406.64
  • ACoS: 5.85%
  • Orders: 3

While the B2C campaign brought in more total sales, it took 222 orders, and more than $1,300 in spend to get there, with an ACoS close to 11%, proving it wasn't cheap to acquire those sales

The B2B campaign, by contrast, drove over $400 in sales from just three orders and less than $24 in spend, with half the ACoS. The takeaway? Fewer clicks, larger carts, and far more efficient spending.

Why Now Is the Best Time to Test

Amazon Business Campaigns are still new. That means this is a first-mover advantage moment:

  • Less competition: Fewer advertisers are bidding on B2B traffic right now.
  • Cheaper clicks: Lower bid pressure means you get more value per dollar.
  • Larger baskets: Business buyers place bigger orders, boosting profitability.
  • Amazon’s backing it: When Amazon promotes a feature, early adopters win.

If your product appeals to both consumers and businesses, you need to be testing this.

Final Thoughts

At AmpliSell, we make it our mission to stay ahead of every Amazon update, not just to stay informed, but to give our clients a performance edge before their competitors catch on.

Amazon Business Campaigns are a sales accelerator and an opportunity to:

  • Expand into higher-margin customer segments: Business buyers order in volume, making each sale more profitable.
  • Drive more revenue with less effort: Bigger orders mean fewer clicks and less spend to reach your goals.

  • Future-proof your Amazon ad strategy: Amazon is clearly investing in B2B. Brands who adopt early build a long-term advantage.

Ready to Explore Amazon Business Campaigns? If you're curious how your catalog might perform in the Amazon B2B space, let’s talk. We’ll help you test it right, and scale it fast. Contact our team today!

About the Author

Amazon Business Campaigns:  The Untapped B2B Goldmine

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